Randomised double-blind trial of recombinant interferon-beta for condyloma acuminatum.

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Randomised double-blind trial of recombinant interferon-beta for condyloma acuminatum.

OBJECTIVE To evaluate the safety and efficacy of two intralesional doses of recombinant human interferon-beta (r-hIFN-beta: Rebif, Ares Serono), given 3 times a week for 3 weeks, in the treatment of condyloma acuminatum. DESIGN A randomised, double-blind, within-patient, placebo-controlled study. SUBJECTS 25 patients (24 males, 1 female) with a history of condyloma acuminatum. Twenty had fa...

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randomised controlled double blind trial

To investigate the effects of supplemental oxygen on cardiac rhythm during gastroscopy, 103 patients aged over 60 were randomised to receive either supplemental oxygen or air at 2 litres/minute during the procedure. Pulse rate, blood pressure, oxygen saturation, and a Holter cardiac trace were monitored before, during, and for one hour after the gastroscopy. A wide range of electrocardiographic...

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Condyloma acuminatum: its histopathological pattern.

Condyloma acuminatum is one of the clinical manifestations of papillomavirus infection. The classical histopathological features are already known and do not constitute a diagnostic problem. Clinically, it has been classified into growth or proliferative, full-expression, and regressive or persistent phases, with the histopathological aspects of these distinct phases being well documented in eq...

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Giant condyloma acuminatum–malignant transformation

Giant condyloma acuminata are associated with malignant transformation in up to 50% of cases, high recurrence rate, and poor prognosis. Treatment strategies have included wide local excision, abdominopelvic resection, and addition of radiotherapy and adjuvant and/or neoadjuvant systemic chemotherapy.

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Condyloma acuminatum of the uterine cervix.

A 23-year-old woman gave a history of intermittent post-coital vaginal spotting, and a Papanicolaou smear indicated the presence of a low-grade squamous intraepithelial lesion and cellular changes due to the cytopathic effect of human papillomavirus (HPV) infection. Colposcopic examination showed a circumferential exophytic lesion (Fig 1). Multiple biopsies were performed; histological examinat...

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ژورنال

عنوان ژورنال: Sexually Transmitted Infections

سال: 1996

ISSN: 1368-4973

DOI: 10.1136/sti.72.2.111